Because each patient is unique, wrinkle improvement requires individualized strategies. Overall improvement of fine wrinkles is often best achieved with laser skin resurfacing. “Frown lines” and “smile lines” improve with Botox treatments, while lip lines may require collagen fillers. Wrinkle prevention is achieved with a home-based medical skin care program. With all of these tools at hand, we can design a safe, effective and individualized strategy for wrinkle improvement and prevention for each of our patients.